Use of antidepressants increase the risk of death by 33 percent, according to an article published in Medicalxpress,  as they block the absorption of serotonin by organs – such as the heart, kidneys, lungs and liver – that require serotonin for proper functioning. ” I think people would be much less willing to take these drugs,” said study co-author Marta Maslej, “if they were aware how little is known about their impact outside of the brain, and that what we do know points to an increased risk of death.”